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Ketamine Therapy: Intramuscular (IM) vs Intravenous (IV)

When it comes to administering ketamine, there are two primary methods: intramuscular (IM) and intravenous (IV). Understanding the differences between these two approaches is crucial for individuals seeking relief and considering the best treatment options. Here are the distinctions between the two treatment options and their implications for management.


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Intramuscular Ketamine Injection Treatment:

  • IM involves injecting the medication directly into the muscle tissue, typically in the upper arm. The injection is quick & straightforward, making it a preferred option for some individuals.

  • Once administered, ketamine enters the bloodstream rapidly through the muscle tissue, leading to a quicker onset of effects compared to IV injections.

  • IM ketamine tends to have a shorter duration of action compared to IV. If requested by the patient, a second booster can be given to prolong the treatment period.

  • IM ketamine may be preferred for individuals who are uncomfortable with IV procedures or those who prefer a faster onset of action.

  • Studies have shown that IM ketamine can be effective in rapidly alleviating symptoms of depression, anxiety, and PTSD, with some patients experiencing improvement within hours of treatment.

  • Research suggests that intramuscular ketamine may have comparable efficacy to intravenous administration in terms of symptom relief and duration of effects.


Intravenous Ketamine Treatment:

  • IV ketamine entails administering the medication directly into the bloodstream through a vein, typically in the arm.

  • IV administration allows ketamine to enter the bloodstream gradually, leading to a slower onset of effects compared to IM injections.

  • IV ketamine boasts a prolonged duration of action compared to intramuscular administration. The infusion is carefully calibrated to specific time intervals and can be adjusted or halted to tailor the experience for personalized effects.

  • IV ketamine may be preferred for individuals seeking relief from severe symptoms or those who prefer a slower onset of action.

  • Clinical trials have demonstrated significant and sustained improvements in mood and overall functioning among patients receiving IV ketamine infusions.


Which Method is Right For You?

Intramuscular and intravenous ketamine treatments offer valuable options for individuals grappling with depression, anxiety, PTSD, chronic pain, and other mental health challenges. While both methods have shown efficacy in clinical settings, the choice between intramuscular and intravenous administration may depend on various factors, including patient preference, medical history, and treatment goals. As research in this field continues to evolve, it is essential for patients and healthcare providers to stay informed and collaborate in exploring the most suitable treatment approach for each individual's needs.



For more information about what Luna offers including an overview of treatment, risks of treatment, and cost, please Contact Us.


Disclaimer: This blog post serves as a mere glimpse into the serene world of ketamine-assisted therapy. It's important to remember that consulting with a qualified healthcare professional is the first step to determining if this journey is right for you. Explore reliable resources and studies to gather more information and make informed decisions about your mental well-being.





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